Enhancing bone healing and regeneration: present and future perspectives in veterinary orthopaedics.

نویسندگان

  • G Vertenten
  • F Gasthuys
  • M Cornelissen
  • E Schacht
  • L Vlaminck
چکیده

Methods currently used to restore bone defects in human and veterinary orthopaedics are often not satisfactory. This is especially the case in the healing of large, irregular defects which result in the formation of tissues with inferior qualities compared to the original structures. For these reasons, several new approaches are currently being explored to improve bone healing capacities in different situations. This review will examine the different techniques used to enhance bone regeneration, highlighting both experimental and clinically applicable methods with regard to veterinary orthopaedics.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Immune System and Bone Regeneration.

Kenneth A. Johnson bone, resulting in delayed or non-union is a vexing clinical problem in all species of animals. Recently, the focus of attention in orthopaedics has been on the treatment of fractures by bone grafts, mesenchymal stem cells, growth factors, biomaterials and improved mechanical environment, either alone or in some combination. These therapies have produced clearly demonstrable ...

متن کامل

Experimental study on healing of long bone defects treated with fibrin membrane enriched with platelet growth factors and periosteal mesenchymal stem cells in rabbit: radiographical and histopathological evaluations

The present study was designed to evaluate the effects of platelet growth factors and periosteal mesenchymal stem cells on bone healing process, radiographically. Forty male White New Zealand rabbits in five equal groups were used in this study. A 2 mm full thickness bone defect was made in left radial bone of each animal. In group A (control) the defect was left with no medical intervention. I...

متن کامل

Comparison of Autogenic Costal Cartilage with Chitosan Scaffold in Canine Humeral Defect Healing

Objective- Current trends emphasize the acceleration of fracture healing on the ground that in doing so, the limitation of mobility and complications associated with recovery period are reduced. The present study aims to compare autogenic costal cartilage with Chitosan scaffold in canine humeral defect healing. Design- Experimental study Animal-15 adult male dogs Procedures-...

متن کامل

Evaluation of Influence of Zeolite/Collagen Nanocomposite (ZC) and Hydroxyapatite (HA) on Bone Healing: A Study on Rabbits

Bone healing is still a great challenge in orthopedic surgery and clinical practice. There is a dearth of research investigating the effect of Zeolite/Collagen (ZC) nanocomposite on bone regeneration. In the present study, a critical segmental defect of the rabbit femur was repaired using defects in femurs repaired by ZC nanocomposite, and the effects were examined histologically. In total, 45 ...

متن کامل

Evaluation of the effects of autologous adipose derived mesenchymal stem cells in combination with polyacrylamide hydrogel and nanohydroxyapatite scaffolds on healing in rabbit critical-sized radial bone defect model

Objective: In this study, the bone regeneration ability of polyacrylamide hydrogel and nanohydroxyapatite scaffolds (PAAH/NHA) and stem cells derived from adipose tissue (ADSCs) in the healing of critical sized bone defects in rabbit radius were assessed. Animals and procedures: 12 New Zealand white male rabbits were divided into 3 groups. The rabbits were anesthetized and 15 mm bone def...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Veterinary and comparative orthopaedics and traumatology : V.C.O.T

دوره 23 3  شماره 

صفحات  -

تاریخ انتشار 2010